| # | VW | W | Artiest | Titel | Label | Distributeur | HP |
|---|
| 1 | NEW | 1 | Natalia & Gabriel Rios | Hallelujah | ARS | UNIVERSAL | 1 |
| 2 | 1 | 7 | Yeah Yeah Yeahs | Heads Will Roll | GEFFEN | UNIVERSAL | 1 |
| 3 | 2 | 10 | Owl City | Fireflies | REPUBLIC | UNIVERSAL | 2 |
| 4 | 3 | 4 | The Opposites feat. Gers & Sef | Broodje bakpao | TOP NOTCH | UNIVERSAL | 3 |
| 5 | 4 | 13 | Daan | Icon | PIAS | PIAS | 2 |
| 6 | 5 | 15 | The Black Eyed Peas | Meet Me Halfway | INTERSCOPE | UNIVERSAL | 1 |
| 7 | 6 | 20 | Absynthe Minded | Envoi | KEREMOS | PIAS/BANG! | 1 |
| 8 | 7 | 16 | Ke$ha | TiK ToK | RCA | SONY | 4 |
| 9 | 9 | 12 | Edward Maya & Vika Jigulina | Stereo Love | ARS | UNIVERSAL | 8 |
| 10 | 10 | 12 | Jay-Z + Alicia Keys | Empire State Of Mind | ATLANTIC | WARNER | 4 |
| 11 | 20 | 2 | David Guetta feat. Kid Cudi | Memories | VIRGIN | EMI | 11 |
| 12 | 8 | 13 | Lady Gaga | Bad Romance | INTERSCOPE | UNIVERSAL | 2 |
| 13 | 19 | 14 | Das Pop | Never Get Enough | 541/NEWS | PIAS/NEWS | 9 |
| 14 | 11 | 30 | The Black Eyed Peas | I Gotta Feeling | INTERSCOPE | UNIVERSAL | 1 |
| 15 | 16 | 3 | Tocadisco & Nadia Ali | Better Run | MOSTIKO | CNR | 15 |
| 16 | 12 | 3 | Alexandra Burke feat. Flo Rida | Bad Boys | SYCO | SONY | 12 |
| 17 | 29 | 2 | Iyaz | Replay | WARNER BROS. | WARNER | 17 |
| 18 | 15 | 10 | Lily Allen | Not Fair | REGAL | EMI | 15 |
| 19 | 24 | 4 | Pitbull feat. Akon | Shut It Down | J | SONY | 19 |
| 20 | 18 | 2 | Channel Zero | Black Flowers | ROADRUNNER | CNR | 18 |
| 21 | 45 | 2 | Dennis Ferrer | Hey Hey | DEFECTED | PIAS/NEWS | 21 |
| 22 | 13 | 7 | The Temper Trap | Sweet Disposition | INFECTIOUS | PIAS | 6 |
| 23 | 14 | 14 | Agnes | On And On | BIP | BIP | 8 |
| 24 | 33 | 4 | AnnaGrace | Love Keeps Calling | SINUZ/NEWS | PIAS/NEWS | 23 |
| 25 | NEW | 1 | Justin Timberlake & Matt Morris feat. Charlie Sexton | Hallelujah | MTV NETWORKS | UNIVERSAL | 25 |
| 26 | 37 | 2 | Bingo Players | Devotion | MOSTIKO | CNR | 26 |
| 27 | 27 | 4 | Jason Derulo | Whatcha Say | WARNER BROS. | WARNER | 27 |
| 28 | 23 | 13 | Mika | Rain | CASABLANCA | UNIVERSAL | 5 |
| 29 | 26 | 12 | Rihanna | Russian Roulette | DEF JAM | UNIVERSAL | 5 |
| 30 | 21 | 7 | Madonna vs. David Guetta | Revolver (One Love Remix) | WARNER BROS. | WARNER | 21 |
| 31 | NEW | 1 | Admiral Freebee | Always On The Run | PLAYOUT! | PIAS | 31 |
| 32 | NEW | 1 | Wildboyz feat. Ameerah | The Sound Of Missing You | ARS | UNIVERSAL | 32 |
| 33 | 22 | 11 | Fake Blood | I Think I Like It | 541/NEWS | PIAS/NEWS | 9 |
| 34 | 31 | 5 | Florence + The Machine | You've Got The Love | ISLAND | UNIVERSAL | 31 |
| 35 | 47 | 2 | 3OH!3 feat. Katy Perry | Starstrukk | ATLANTIC | WARNER | 35 |
| 36 | 28 | 27 | David Guetta feat. Akon | Sexy Bitch | VIRGIN | EMI | 1 |
| 37 | 25 | 15 | Mumford & Sons | Little Lion Man | V2 | V2 | 4 |
| 38 | 40 | 7 | Robbie Williams | You Know Me | VIRGIN | EMI | 17 |
| 39 | 17 | 7 | vtmKzoom | Het vtmKzoom lied | ARS | UNIVERSAL | 2 |
| 40 | 42 | 10 | Isbells | As Long As It Takes | ZEAL | KONKURRENT | 22 |
| 41 | 35 | 17 | Mike Candys & Jack Holiday | Insomnia | BIP | BIP | 9 |
| 42 | 38 | 7 | Funk-K | Dirty Cash 2010 | BIP | BIP | 29 |
| 43 | 30 | 4 | Timbaland feat. Nelly Furtado & SoShy | Morning After Dark | INTERSCOPE | UNIVERSAL | 30 |
| 44 | 34 | 4 | Anouk | Woman | DINO | EMI | 32 |
| 45 | 43 | 9 | Jay Sean feat. Lil Wayne | Down | DEF JAM | UNIVERSAL | 32 |
| 46 | 39 | 2 | Jay-Z, Bono, The Edge & Rihanna | Stranded (Haiti mon amour) | MTV NETWORKS | UNIVERSAL | 39 |
| 47 | 32 | 2 | Eels | A Line In The Dirt | VAGRANT | V2 | 32 |
| 48 | NEW | 1 | Cheryl Cole | Fight For This Love | POLYDOR | UNIVERSAL | 48 |
| 49 | NEW | 1 | Coldplay | A Message 2010 | MTV NETWORKS | UNIVERSAL | 49 |
| 50 | 36 | 15 | Daan | Exes | PIAS | PIAS | 17 |
